Vitamin D and Systemic Lupus Erythematosus


In recent paper, by Diane Kamen et.al,  was published looking at the connection of vitamin D and systemic lupus erythematosus.  It contained a very nice review of the relationship between vitamin D and the immune system, and in this article particularly autoimmune disease.  It was noted that vitamin D definitely benefits collegen — induced arthritis in mice.  It also reviews international studies and american studies in humans. The authors specifically state that one study in Europe has found a significant correlation between vitamin D levels and lupus disease activity.

 

The conclusion of the authors is that "The physiologic and clinical significance of vitamin D deficiency in SLE is not entirely known". They recommend, that more prospective studies be done to vitamin D and lupus.  The authors expect that correcting vitamin D deficiency will lead to better outcomes for lupus patients.

 

As I pointed out several times in my book there is absolutely nothing wrong with normalizing everybody’s vitamin D level and seeing what the clinical results are from doing that!  I have been  delighted with the results of normalizing vitamin D in so many medical conditions in my practice, including systemic lupus erythematosus.

 

Reference

 

Curr Opin Rheumatol. 2008;20(5):532-537  (PMID 18698173)

 


 

 

 

 

8 Responses to “Vitamin D and Systemic Lupus Erythematosus”


  1. 1 Helga Rhein

    Dear Dr. Soram,
    What would you call normalizing the vitamin D level? (in respect of blood values)
    Thanks very much
    Helga

  2. 2 Elizabeth Goodrich

    I have had systemic Lupus Erythematosus for 12 years. I have always taken calicum with V D, but in the past two month, I had a blood test and my Vit D level is low, was glad to find information on this as I did not understand what is the conection with my lupus and Vitamin D. Am so glad to find this

  3. 3 Dr. Soram

    Thank you Elizabeth! I am glad you are correcting your D level ! Let me know if you see improvement over a few months

  4. 4 Dr. Soram

    Helga
    “Normal” is now accepted as over 30 ng/ml but integrative doctors including myself as I talk about in the book recommend 40-70 ng/ml . Hope that helps

  5. 5 geoff daum

    Yep – I would agree with that.. Thanks for the line.

  6. 6 jenn

    I have fibromyalgia and have been diagnosed now for two years. I also have pernecious anemia, along with post partial thyroidectomy,. I have had some new symptoms such as leg weakness tremors when bear weight . Called my Dr tell her the new symptoms and she stated my vitamin d level was 8., and she stated she mailed me a prescription for that, and to not worry? But with the severe pain and new symptoms I am concerned. Can anyone shed some light on this?

  7. 7 Dr. Soram

    Jenn
    Please repost your question to the new blog HERE so I can answer it
    Thank you
    Dr Soram

  8. 8 Dr. Soram

    Jenn
    some of your pain may be due to the very low vitamin D level. I would listen to your doctor and take the vitamin D pills she sent you and see how you feel in 8-10 weeks.
    Dr Soram

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