Comments on: Link between Heart Disease and Vitamin D Gene http://blog.vitamindrevolution.com/2009/12/20/link-between-heart-disease-and-vitamin-d-gene/ A higher level of health with Vitamin D Thu, 20 May 2010 01:50:25 -0600 http://wordpress.org/?v=2.8.4 hourly 1 By: Dr. Soram http://blog.vitamindrevolution.com/2009/12/20/link-between-heart-disease-and-vitamin-d-gene/comment-page-1/#comment-541 Dr. Soram Sun, 07 Feb 2010 01:56:09 +0000 http://blog.vitamindrevolution.com/?p=192#comment-541 Robert! I can tell you did not read my book! But, let me give you a quick answer. The proper blood test for vitamin D is the 25 hydroxy vitamin D test ! taking vitamin D orally will definitely raise your blood levels. I hope that's helpful to you. Dr. Soram Robert!
I can tell you did not read my book! But, let me give you a quick answer. The proper blood test for vitamin D is the 25 hydroxy vitamin D test !

taking vitamin D orally will definitely raise your blood levels.

I hope that’s helpful to you. Dr. Soram

]]> By: Robert http://blog.vitamindrevolution.com/2009/12/20/link-between-heart-disease-and-vitamin-d-gene/comment-page-1/#comment-486 Robert Fri, 15 Jan 2010 20:53:55 +0000 http://blog.vitamindrevolution.com/?p=192#comment-486 Hello Dr. Soram, Is there a direct test available for the quantification of Vit D3 in blood/serum? Do you think clinicians would prefer D3 tests or 25(OH)D tests? What would you consider to be more valuable? By D3, I mean cholecalciferol. Regards Robert Hello Dr. Soram,

Is there a direct test available for the quantification of Vit D3 in blood/serum? Do you think clinicians would prefer D3 tests or 25(OH)D tests? What would you consider to be more valuable?

By D3, I mean cholecalciferol.

Regards

Robert

]]> By: Dr. Soram http://blog.vitamindrevolution.com/2009/12/20/link-between-heart-disease-and-vitamin-d-gene/comment-page-1/#comment-482 Dr. Soram Sun, 10 Jan 2010 18:58:35 +0000 http://blog.vitamindrevolution.com/?p=192#comment-482 Great--glad you posted this and it is very important! Also the reduction in inflammation due to statins may be another mechanism of how they work Dr Soram Great–glad you posted this and it is very important!
Also the reduction in inflammation due to statins may be another mechanism of how they work
Dr Soram

]]> By: vince http://blog.vitamindrevolution.com/2009/12/20/link-between-heart-disease-and-vitamin-d-gene/comment-page-1/#comment-464 vince Tue, 22 Dec 2009 18:26:13 +0000 http://blog.vitamindrevolution.com/?p=192#comment-464 A few additional studies of interest. Am J Cardiol. 2007 Oct 15 " Effects of Atorvastatin on vitamin D levels in patients with acute ischemic heart disease." ........ "In conclusion, atorvastatin increases vitamin D levels. This increase could explain some of the beneficial effects of atorvastatin at the cardiovascular level that are unrelated to cholesterol levels....PMID: 17398180 [PubMed] Cardiovasc Drugs Ther. 2009 Aug23 Increased levels of 25 hydroxyvitamin d and 1,25-dihydroxyvitamin D after rosuvastatin treatment: a novel pleiotropic effect of statins? Yavuz B, Ertugrul DT, Cil H, Ata N, Akin KO, Yalcin AA, Kucukazman M, Dal K, Hokkaomeroglu MS, Yavuz BB, Tutal E. "..... CONCLUSION: This study has shown an effect of rosuvastatin on vitamin D metabolism, with an increase in both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. This may be an important pleiotropic effect whereby rosuvastatin reduces mortality in patients with coronary artery disease. Further studies are needed to clarify the relationship between statins and vitamin D metabolism. PMID: 19543962 [PubMed - in process] Another published in Circulation " "1,25(OH)2 Vitamin D Inhibits Foam Cell Formation and Suppresses Macrophage Cholesterol Uptake in Patients With Type 2 Diabetes Mellitus" Interesting A few additional studies of interest. Am J Cardiol. 2007 Oct 15
” Effects of Atorvastatin on vitamin D levels in patients with acute ischemic heart disease.”
…….. “In conclusion, atorvastatin increases vitamin D levels. This increase could explain some of the beneficial effects of atorvastatin at the cardiovascular level that are unrelated to cholesterol levels….PMID: 17398180 [PubMed]

Cardiovasc Drugs Ther. 2009 Aug23
Increased levels of 25 hydroxyvitamin d and 1,25-dihydroxyvitamin D after rosuvastatin treatment: a novel pleiotropic effect of statins?
Yavuz B, Ertugrul DT, Cil H, Ata N, Akin KO, Yalcin AA, Kucukazman M, Dal K, Hokkaomeroglu MS, Yavuz BB, Tutal E.

“….. CONCLUSION: This study has shown an effect of rosuvastatin on vitamin D metabolism, with an increase in both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D. This may be an important pleiotropic effect whereby rosuvastatin reduces mortality in patients with coronary artery disease. Further studies are needed to clarify the relationship between statins and vitamin D metabolism.

PMID: 19543962 [PubMed - in process]

Another published in Circulation ” “1,25(OH)2 Vitamin D Inhibits Foam Cell Formation and Suppresses Macrophage Cholesterol Uptake in Patients With Type 2 Diabetes Mellitus”

Interesting

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